Scientific Session 1
CMI-P-38
Bengang Xing
Hong Kong Polytechnic Univeristy
Chair Professor, The Global STEM Scholar
China
Chemical biology, Molecular probe & imaging, Bio-labeling, Molecular therapeutics, Nano-theranostics
B.S., 1994, Xinjiang Normal University; Ph.D., 2000, Nanjing University (advisor: Tang Wenxia); Postdoctoral Training, 2000-2003, HKUST (advisor: XU Bing); 2003-2005 UCLA/Standford (advisor: RAO Jiang hong), Assistant Professor, 2006-2011, NTU; Associate Professor (Tenured), 2011-2019, NTU; Professor, 2019-present, NTU; Chair Professor/the Global STEM Scholar, 2024-present, the Hong Kong Polytechnic University;
“Enzyme-activated Orthogonal Proteolysis Chimera for Tumor Microenvironment-responsive Immunomodulation”, Caixia Sun,† Songhan Liu,† Jun Wei Lau,‡ Hanyu Yang,† Yun Chen,† Bengang Xing†*, Angew. Chem. Intl. Ed, 2025, 137, e202423057
“A Nitroreductase-activatable Metabolic Reporter for Covalent Labeling of Pathological Hypoxia Cells in Tumorigenesis,” Zhimin Wang†*, Jun Wei Lau†, Ziheng Ren, Zhiyuan Gong, Xiaogang Liu, Bengang Xing*, Angew. Chem. Intl. Ed, 2024, 64, e202411636.
“Enzymes in Synergy: Bacteria Specific Molecular Probe for Locoregional Imaging of Urinary Tract Infection in vivo”, Y. H. Xin+, G. Kwek+, X. An+,C. Sun, S. Liu, S,. Ng, S. Lingesh, L. Jiang, G. Liu*, B. G. Xing*, Angew. Chem. Intl. Ed, 2024, 64, e202406843. 'VIP" paper
“Nanoparticles-mediated Ion Channels Manipulation: From Their Membrane Interactions to Bioapplications.” Q. Huang, W. Zhu, X. Gao, X. Liu, Z. Zhang*, B. G. Xing*, Adv Drug Delivery Rev., as Theme Issue & Guest Editor, Article 114763, 2023.; Preface Article 114991, 2023.
“Hypoxia Deactivates Epigenetic Feedbacks via Enzyme-derived Clicking Proteolysis Targeting Chimeras”; D. C. Thang, J. Lau, C. Sun, S. Liu, K, Kha, S. Lim, X. Liu, T. Carney, X. Wang*, B. G. Xing* Sci. Adv. 2022, 8 (50), abq2216
“Cyanine-Dyad Molecular Probe for Simultaneous Profiling of Multiple Radical Species Evolution in Bacterial Infection". Z. Wang, C. Thang, W. Zhong, J. Lau; G. Kwek; M. Chan-Park, B. G. Xing*, Angew. Chem. Intl. Ed, 2021, 60, 16900, Highlight as VIP paper
“Multispectral Optoacoustic Imaging of Dynamic Redox Correlation and Pathophysiological Progression Utilizing Upconversion Nanoprobes.” X. Ai, Z. Wang, H. Cheong, Y. Wang, R. Zhang, J. Lin, Y. Zheng, M. Gao*, B. G. Xing*. Nat. Commun. 2019, 10, 1087
“Remote Regulation of Membrane Channel Activity by Site-specific Localization of Lanthanide doped Upconversion Nanocrystals”. X. Ai, L. Lyu, Y. Zhang, Y. Tang, J. Mu, F. Liu, Y. Zhou, Z. Zuo, G. Liu*, B. G. Xing*, Angew. Chem. Intl. Ed, 2017, 56, 3031.
Molecular probe, innovative techniques
