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Scientific Session 6

CMI-P-16

Mikiko Sodeoka

RIKEN

Director of Center for Sustainable Resource Science

Japan

Raman imaging, Affinity labeling, Cell death

ACADEMIC CAREER

1983, M. Pharm., Chiba Univ. (advisor: Toru Hino); 1989, D. Pharm, (advisor: Masakatsu Shibasaki); 1983-1986, Research Associate, Sagami Chemical Research Center; 1986-1990, Assistant Professor, Hokkaido Univ.; 1990-1992, Postdoctoral Fellow, Harvard Univ. (advisors: E. J. Corey & Gregory L. Verdine); 1992-1995, Assistant Professor, The Univ. of Tokyo; 1996-1999, Group Leader, Sagami Chemical Research Center; 1999-2000, Associate Professor, The Univ. of Tokyo; 2000-2006, Professor, Tohoku Univ.; 2006-2024, Chief Scientist, RIKEN; 2013-present, Group Director and 2025-present, Director RIKEN Center for Sustainable Resource Science.

SELECTED PUBLICATIONS
  • Simple Purification of Small-Molecule-Labeled Peptides via Palladium Enolate Formation from β-Ketoamide Tags. K. Hayamizu et al. Chem. Sci. 2023, 14, 8249

  • Raman Spectroscopy for Chemical Biology Research. K. Dodo et al. J. Am. Chem. Soc. 2022, 144, 19651

  • Dual targeting of DDX3 and eIF4A by the translation inhibitor Rocaglamide A. M. Chen, et al. Cell Chem. Biol. 2021, 28, 475.

  • Development of a Water-Soluble Indolylmeleimide Derivative IM-93 Showing Dual Inhibition of Ferroptosis and NETosis. K. Dodo, et al. ACS Med. Chem. Lett. 2019, 10, 1272

  • Alkyne-tag SERS Screening and Identification of Small-molecule-binding Sites in Protein. J. Ando et al. J. Am. Chem. Soc. 2016, 138, 13901

  • Sphingomyelin Distribution in Lipid Rafts of Artificial Monolayer Membranes Visualized by Raman Microscopy. J. Ando, et al. Proc. Nat. Acad. Sci. 2015, 112, 4546

  • Turn-ON Fluorescent Affinity Labeling Using a Small Bifunctional O-Nitrobenzoxadiazole Unit: Selective Labeling and Imaging of Target Protein, T. Yamaguchi et al. Chem. Sci. 2014, 5, 1021

  • Alkyne-tag Raman imaging for visualization of mobile small molecules in live cells , H. Yamakoshi et al. J. Am. Chem. Soc. 2012, 134, 20681

WHY MY LAB?

My lab can offer affinity labeling method (NBD method) and Raman imaging method.

CMI-P-01

Motonari Uesugi

Kyoto University

Japan

Chemical biology, Chemoproteomics, Self-assembly, Chemical immunology

CMI-P-02

Kazuya Kikuchi

The University of Osaka

Japan

Molecular imaging, MRI, Fluorescent probes, Photo-activation

CMI-P-03

Takeaki Ozawa

The University of Tokyo

Japan

Fluorescence imaging, Bioluminescence analysis, Optogenetics

CMI-P-04

Midori Arai

Keio University

Japan

Natural products chemistry, Chemical biology, Organic chemistry

CMI-P-05

Takayoshi Suzuki

The University of Osaka

Japan

Medicinal chemistry, Epigenetics, New modality

CMI-P-06

Hideaki Kakeya

Kyoto University

Japan

Natural product chemistry, Chemical biology, Medicinal chemistry

CMI-P-07

Youhei Sohma

Wakayama Medical University

Japan

Peptide chemistry, Amyloid, Catalysis

CMI-P-08

Hiroyuki Nakamura

Institute of Science Tokyo

Japan

Medicinal chemistry, Cancer therapy, Protein modification

CMI-P-09

Akio Ojida

Kyushu University

Japan

Chemical biology, Medicinal chemistry

CMI-P-10

Shinya Hagihara

RIKEN

Japan

Plant chemical biology, Sustainable agriculture, New breeding technology

CMI-P-11

Masaki Kita

Nagoya University

Japan

Chemical biology, Natural products chemistry, Bioorganic chemistry

CMI-P-12

Go Hirai

Kyushu University

Japan

Bioorganic chemistry, Organic synthesis, Glycans, Lipids

CMI-P-13

Tasuku Hirayama

Gifu Pharmaceutical University

Japan

Imaging, Fluorescent probes, Bioinorganic chemistry

CMI-P-14

Fumika Yakushiji

Nagasaki University

Japan

Chemical epigenetics, Chemical probes, Synthetic organic chemistry, Peptide, Small molecules

CMI-P-15

Yuki Goto

Kyoto University

Japan

Peptides, Natural Products, Biosynthesis

CMI-P-16

Mikiko Sodeoka

RIKEN

Japan

Raman imaging, Affinity labeling, Cell death

CMI-P-17

Minoru Yoshida

RIKEN

Japan

Chemical genomics, Drug discovery, Target identification

CMI-P-18

Fumi Nagatsugi

Tohoku University

Japan

Nucleic acids chemistry, Organic chemistry, Chemical biology

CMI-P-19

Masaya Imoto

Juntendo University

Japan

Cell biology, Biochemistry, Chemical biology

CMI-P-20

Ho Jeong Kwon

Yonsei University

South Korea

Chemical biology, Chemical genomics, Chemical proteomics, Organelle interaction, Autophagy

CMI-P-21

Yongseok Choi

Korea University

South Korea

Medicinal chemistry, Autoimmune diseases, Fibrosis

CMI-P-22

Sun Choi

Ewha Womans University

South Korea

AI and computer-aided drug design, Computational medicinal chemistry, Drug discovery

CMI-P-23

Young-Tae Chang

POSTECH

South Korea

Chemical based aging research, Fluorescent imaging, Fluorescent probe, Cell selective probe, Reverse aging

CMI-P-24

Ja-Hyoung Ryu

UNIST

South Korea

Peptide assembly, PPI mimic, Supramolecular chemistry

CMI-P-25

Jun-Seok Lee

Seoul National University

South Korea

Fluorescent probe, Chemoproteomics, Drug mode of action

CMI-P-26

Hyun-Suk Lim

POSTECH

South Korea

Drug discovery, Targeted protein degradation, DNA-encoded library

CMI-P-27

Yan-Mei Li

Tsinghua University

China

PTMs of protein, Vaccine, cGAS-STING

CMI-P-28

Ming-Wei Wang

Research Center for Deepsea Bioresources

China

GPCR, PI3K alpha, Structural pharmacology, Drug discovery, Nanobody

CMI-P-29

Dan Yang

Westlake University

China

Disease mechanism, Fluorescent sensors, Molecular imaging, Proteomics, Drug development

CMI-P-30

YongXiang Chen

Tsinghua University

China

Protein and peptide chemistry, Protein modification, Phosphorus chemical biology, Biomedical application

CMI-P-31

Xiaoguang Lei

Peking University

China

Natural product, Chemical genetics, Drug discovery, Biosynthesis, Biocatalysis

CMI-P-32

Qian Zhao

Hong Kong Polytechnic Univeristy

China

Proteomics, Natural novel peptides, Mass spectrometry

CMI-P-33

Dehua Yang

Shanghai Institute of Materia Medica, CAS

China

GPCRs, GLP-1R, High-throughput screening, Signal transduction, Receptor pharmacology

CMI-P-34

Huan Wang

Nanjing University

China

Peptide, Protein, Enzyme, Natural product, Synthetic biology

CMI-P-35

Xin Zhang

Westlake University

China

Chemical biology, Biological chemistry, Fluorescent microscopy, Synthetic chemistry

CMI-P-36

Liyun Zhang

Nankai University

China

Synthetic biology, Biosensor, Biocatalysis

CMI-P-37

Zou Peng

Peking University

China

Proximity labeling, Voltage imaging, Neuroscience, Membraneless organelles

CMI-P-38

Bengang Xing

Hong Kong Polytechnic Univeristy

China

Chemical biology, Molecular probe & imaging, Bio-labeling, Molecular therapeutics, Nano-theranostics

CMI-P-39

Jing Yu

Tsinghua University

China

Biophysics, Assembly of biomacromolecules, Condensation of biomolecules

CMI-P-40

Shi-Zhong Luo

Beijing University of Chemical Technology

China

Bioactive peptide, Cell surface protein phase separation, Peptide drug, Drug delivery

CMI-P-41

Sandeep Verma

IIT Kanpur

India

Chemical neuroscience, Microfluidic devices, New antibiotics

CMI-P-42

Govindaraju Thimmaiah

JNCASR

India

Neurodegenerative diseases, Redox biology, Ferroptosis and cuproptosis, Neuroinflammation, Theranostics (diagnostic therapy)

CMI-P-43

Eylon Yavin

The Hebrew University

Israel

PNA, RNA sensors, Antisense, Fluorogenic dyes

CMI-P-44

Micha Fridman

Tel Aviv University

Israel

Antimicrobial agents, Fluorescent antifungal probes, Drug resistance and tolerance, Subcellular localization of small molecules

CMI-P-45

Doron Shabat

Tel Aviv University

Israel

Chemiluminsence, Molecular sensores, Bioorganic chemistry

CMI-P-46

Yuval Ebenstein

Tel Aviv University

Israel

Genomics and epigenetics, Fluorescence microscopy, Diagnostics

CMI-P-47

Amir Goldbourt

Tel Aviv University

Israel

Solid state nuclear magnetic resonance, Structural virology, NMR methods and developments

CMI-P-48

Chayasith Tao Uttamapinant

VISTEC

Thailand

Genetic code expansion, Liquid-liquid phase separation, Synthetic biology, Plastic waste bioremediation, Infectious diseases

CMI-P-49

Jay Chanat Aonbangkhen

Chulalongkorn University

Thailand

Chemical probes, Fluorescent dyes, Proteomics, Bioactive peptides, Cancer cell signaling

CMI-P-50

Jiranan Chotitumnavee

Mahidol University

Thailand

Epigenetics, Cancers, Pharmacology, Medicinal chemistry

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